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Our Global Vision

At Silence, we aim to transform peoples’ lives around the world by silencing diseases through our precision engineered medicines and driving positive change for the communities around us. As pioneers in the design and development of siRNAs (short interfering RNAs), we are advancing a new generation of medicines to potentially address the needs of patients who have limited or inadequate treatment options.

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Our mRNAi GOLD™ Platform

Our proprietary mRNAi GOLD™ platform harnesses the body’s natural mechanism of RNAi (RNA interference) to create precision medicines designed to silence disease-associated genes. We design our siRNAs with patients in mind – to maximize efficacy, minimize off-target effects and have long duration of action. Through this approach, we are advancing a robust pipeline of wholly owned programs and partnership programs for diseases with high unmet need.

  • natural

    Natural

    Harnesses natural mechanisms present in every cell in the human body

  • durable

    Durable

    Long-lasting gene silencing possible following a single injection

  • precise

    Precise

    siRNA designed to bind only to the target gene

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+8

Pipeline Programs

2

In Clinical Trials

+4

Wholly Owned

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Strategic Collaborations

Our Commitment to Patients

We see the patient in every action. Their needs drive our discoveries and relentless commitment to deliver life-changing therapies as efficiently as possible. We know that patients are waiting and that responsibility inspires us to do our best every day.

commitment

Join a Great Place to Work®

We’re a vibrant, growing, global company with a start-up mindset. One that begins with doing what we love and ends with fulfilling our vision. We’re seeking smart, fun and passionate people to join our expanding team.