About Us

Silence Therapeutics develops a new generation of medicines by harnessing the body’s natural mechanism of RNA interference, or RNAi, within its cells.

Our proprietary technology can selectively inhibit any gene in the genome, specifically silencing the production of disease-causing proteins. Using our enabling delivery systems, we have achieved an additional level of specificity by delivering our therapeutic RNA molecules exclusively to target cells. Silence’s proprietary RNA chemistries and delivery systems are designed to improve the stability of our molecules and enhance effective delivery to target cells, providing a powerful modular technology well suited to tackle life-threatening diseases.


Our strategy is to develop RNAi-based therapeutics to tackle life-threatening diseases. We strive to do this in a risk-diversified manner to maximise our probability of success.

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Our People

Well equipped to drive execution

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Management Team

Our management team is highly experienced in a variety of relevant sectors, from molecular biology and genetics to finance and investment banking. This combination of skillsets enables the team to effectively execute our business plan.

Strong leadership

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Board of Directors

Our Board provides oversight to ensure that the highest Corporate Governance standards are maintained, applies internal financial controls and approves the Company’s policy and strategy.

Access to distinguished experts and KOLs


Scientific Advisory Board

We aim to stay in the frontline of the fast-moving field of oligonucleotide therapeutics. Our Scientific Advisory Board (SAB) is a group of world-leading experts in drug discovery and clinical development with particular expertise in the rare disease space. The SAB challenges us to excel at siRNA molecular design, drug discovery, and development

Corporate responsibility

Silence strives to conduct its business in an ethical, responsible and transparent manner. We set high standards of conduct and behaviour and expect all our employees, officers and directors to adhere to those standards. Partners, employees, customers and suppliers can all expect the highest standards of professional conduct when dealing with our Company. The Board of Directors is responsible for setting and reviewing the Company’s values and standards.

Silence recognises and accepts its responsibility as an employer to maintain, as far as is reasonably practicable, the safety and health of its employees and of other persons who may be affected by its activities. Silence Therapeutics is an equal opportunities employer.



Our mission is to continue to build Silence as a global leader in the field of RNAi therapeutics, where our technology can create a new generation of approaches to address unmet medical need and improve outcomes for patients.

If you are a passionate individual with relevant experience, and a desire to subscribe to our goals, we would be delighted to hear from you.